By default in Kaspersky Internet Security 2010 and Kaspersky Antivirus 2010, option to register using .key file is missing and most of the Kaspersky users who have updated to 2010 series are finding it difficult to activate using a .key file as the option to activate KIS 2010 or KAV 2010 is completely missing in 2010 series.
It either asks you to activate using a genuine key by registering online or to activate a 30-day trial period online.
But if you have a .key and want to register using that, here’s a little trick to open “Activate using key file” option in kaspersky 2010.
1. Open “License Manager”
2. Click “Activate New License” from the two options given.
3. Choose “Activate Commercial License”
and Enter your Registration code.
4. Click “Next”
You’ll see a dialogue box, saying :
“Activation code is not compatible with this application… blah blah blah…”
Just Hit “OK”
On the very next screen, you will be given the option to browse for the key file to activate the product! 
Just click “Browse” to browse and apply your activation key file.
See Kaspersky KEY Viewer to check creation/expiry dates of any .key file
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